Caffeine Anhydrous

Caffeine Anhydrous is the dehydrated and purified form of caffeine — without the water present in natural coffee. It is a central nervous system stimulant that acts as a competitive antagonist of adenosine receptors (A1 and A2A). Adenosine is the neurotransmitter responsible for the feeling of tiredness — by blocking its receptors, caffeine reduces fatigue perception, increases alertness and improves mood. The anhydrous form has faster and more precise absorption than coffee — reaching plasma peak in 45–60 minutes.

• Reduced perceived fatigue and increased alertness
• Improved strength, power and endurance
• Enhanced focus and concentration
• Amplified fat oxidation as energy substrate
• Reduced RPE (subjective perception of effort)
• Improved mood and motivation
• Enhances the effect of other supplements (citrulline, beta-alanine)

• •Practitioners of any sport modality
• •People who train early or at low-energy times
• •Those seeking improved focus and cognitive performance
• •Endurance athletes needing to delay fatigue
• •People who want precise caffeine dose control vs. coffee

3–6mg/kg body weight, 45–60 minutes before training. Common dose: 150–300mg. Beginners: start with 100–150mg to assess tolerance. Avoid after 2 PM to not compromise sleep.

Caffeine Anhydrous is the most precise and controllable form of caffeine — you know exactly how much you are taking, unlike coffee (which varies from 60–200mg per cup). Advantages vs. coffee: precise dose, faster absorption, no gastric acid, no additional diuretic. Tolerance develops quickly — cycling is recommended (5 days on / 2 off, or 8 weeks on / 2 weeks off). CYP1A2 gene polymorphism determines if you are a fast or slow caffeine metabolizer — slow metabolizers have greater sensitivity and cardiovascular risk at high doses.

Caffeine is the most studied stimulant in the world and one of the ergogenics with the greatest evidence. Meta-analyses confirm improvements in strength (3–5%), aerobic endurance (2–4%), anaerobic power and RPE reduction. The adenosine mechanism is well established. Studies show that the ergogenic effect persists even in chronic users, although the magnitude is smaller. The caffeine + citrulline + beta-alanine combination has documented additive effect.

Anxiety, tachycardia and tremors at high doses or in sensitive people. Insomnia if taken late. Psychological dependence and withdrawal syndrome (headache, fatigue) after chronic use. Transient hypertension. Interaction with cardiovascular medications. Doses above 400mg/day associated with cardiovascular risk in slow metabolizers (CYP1A2).